Well I'm late to respond, but here it comes. I always shoot 125 Thundersheads. Coming from close to sea level then traveling to altitude things change. T Bombs would take awhile to group even when bow was set up when I left home. To answer the question from where I stand openers are a little more (no, a lot more) forgiving. This could be with your release, rest, or your bow not being tuned or other issues as well. If they are legal and you want to, go for it. They will not expand your effective range as 50+ is still 50+. You make a slight mistake or the animal moves, it's a bad day for everyone.
With that being said, what did you use and how did it go?
Simo